Animal models of Huntington's disease (HD) that utilize 3-nitropropionic acid (3-NPA) in the initiation of oxidative stress
and accelerated brain-aging have been extensively studied. When administered to rodents, 3-NPA irreversibly...
Human reproductive technology; Fertilization in vitro, Human
The purpose of this study was to evaluate the outcome of Intracytoplasmic Sperm Injection (ICSI) in patients with previous unexplained fertilization failure (≤20%) after conventional in vitro fertilization (IVF) in our program and to compare them...
The ability of embryonic stem cells to give rise to all cells comprising the three germ layers – endoderm, mesoderm and ectoderm – highlights a powerful in vivo system for the study of early embryonic development. Human embryonic stem cell...
AMP-dependent kinase (AMPK) is a primary energy sensor that controls energy use and production during metabolic cellular stress, such as hypoxia and nutrient deprivation. AMPK activation results in inhibition of anabolic processes and promotion...
The prophage of bacteriophage P1 is a unit copy plasmid, stable in Escherichia coli during cell division due to its partition system. The active P1 partition system consists of two genes, parA and parB, and a cis-site, parS. ParS contains all of...
Tick-borne diseases have become a principal public health concern in the United States due to the tremendous increase in human contact with deer. This concern has been reflected in Connecticut as well in recent years. With changing demographic...
