A-to-I RNA editing is an enzymatic reaction commonly found in the nervous system of various organisms. The mechanism behind this post-transcriptional modification is the hydrolytic deamination of Adenosine to Inosine by a family of enzymes known as...
Discovering RNA editing sites in model organisms provides an insight into their adaptations in addition to finding potential sites for gene expression regulation. In this study, we focused on the grin1b gene of Zebrafish due to its important...
Prediction of scholastic success; Chemistry -- Study and teaching (Secondary); Algebra
In a New England private, all-male high school, all students are required to take a chemistry course, regardless of their academic course level. Many of the students and their parents believe, if they are not strong in mathematics, that they will...
Scituate Reservoir Watershed (R.I.); Geographic information systems -- Rhode Island -- Scituate Reservoir Watershed; Remote sensing -- Rhode Island -- Scituate Reservoir Watershed; Water -- Pollution -- Rhode Island -- Scituate Reservoir Watershed...
Several years ago, the GIS Department at Fuss & O'Neill, was approached by Rich Blodgett, Manager of Environmental Resources for the Providence Water Supply Board with a request. The Environmental Resources Department of Providence Water, as the...
The Brian Head Formation represents the first widespread pulse of volcanism in the Tertiary of southwestern Utah. In the Casto Canyon area, about 20 km north of Bryce Canyon National Park, silicified beds are found within the upper part of the...
DNA -- Analysis; Nucleotide sequence; Cancer genes
The first methods for sequencing DNA were developed in the mid-1970’s (Strausberg et al. 2008). The sequencing efforts were labor-intensive, slow, and costly (Metzker, 2005). As a result, researchers could sequence only a few base pairs per...
The frizzy (fr) mutation in Mus musculus affects hair structure and formation. Early studies demonstrated that the gene responsible for frizzy assorts to mouse Chromosome 7 along with pink-eyed dilution (p), chinchilla (cch), and shaker-1 (sh-1). ...
The mouse frizzy (fr) mutation arose on a genetically mixed background and was first described by G.D. Snell of The Jackson Laboratory in 1951. Mice carrying this recessive mutation have curly vibrissae which can be observed as early as one to two...
The prophage of bacteriophage P1 is a unit copy plasmid, stable in Escherichia coli during cell division due to its partition system. The active P1 partition system consists of two genes, parA and parB, and a cis-site, parS. ParS contains all of...
The recessive male sterility and histoincompatibility mutation (mshi) in the mouse generates pleiotropic effects on graft transplantation and male reproduction. Previous analysis of backcross mice using a large set of microsatellite markers has...
The RNA molecule is responsible for providing information to the cell to assemble proteins specified by the DNA. A specific type of RNA editing can convert individual adenosines into inosine by an enzyme called adenosine deaminase acting on RNA...
The tick has ability to transmit a greater variety of infectious agents to humans and other animal species than any other blood-feeding arthropod. Feeding over a period of days induces specific host hemostatic, inflammatory, and immune responses....
Transforming growth factor-alpha (TGFa), a member of the endothelial growth
factor (EGF) family of mitogens, was previously thought to exist solely in neoplastic
cells and the quickly dividing cells of a developing fetus. Since then, TGFa...
