The RNA molecule is responsible for providing information to the cell to assemble proteins specified by the DNA. A specific type of RNA editing can convert individual adenosines into inosine by an enzyme called adenosine deaminase acting on RNA...
Percutaneous coronary intervention (PCI) and coronary artery bypass graft (CABG) surgery are two types of revascularization procedures done in patients with single and multi-vessel coronary disease. The purpose of this review of the literature was...
During the last decade, new technologies created a deluge of potential drug targets. Sifting through thousands of potential drug targets is a major industry bottleneck. Pharmaceutical companies can save billions of dollars by identifying most...
The prophage of bacteriophage P1 is a unit copy plasmid, stable in Escherichia coli during cell division due to its partition system. The active P1 partition system consists of two genes, parA and parB, and a cis-site, parS. ParS contains all of...
The frizzy (fr) mutation in Mus musculus affects hair structure and formation. Early studies demonstrated that the gene responsible for frizzy assorts to mouse Chromosome 7 along with pink-eyed dilution (p), chinchilla (cch), and shaker-1 (sh-1). ...
The recessive male sterility and histoincompatibility mutation (mshi) in the mouse generates pleiotropic effects on graft transplantation and male reproduction. Previous analysis of backcross mice using a large set of microsatellite markers has...
The male sterility and histoincompatibility mutant, mshi, results from a recessive mutation that arose spontaneously in the BALB/cBy inbred mouse strain. Using a 402-member BALB/cBy-mshi/mshi (BALB/cBy-mshi C57BL/6J) F1 backcross panel, the...
Postoperative nausea and vomiting (PONV) is a complication of surgery and anesthesia that has major implications in terms of delaying recovery and raising costs through an increase in time and resources necessary for treatment. In addition, PONV...
Receptor-mediated endocytosis as a route of gene delivery shows promise as it is a natural cellular process and allows targeting of ligands to specific cells. A carrier system consisting of two important components: a targetable ligand,...
Discovering RNA editing sites in model organisms provides an insight into their adaptations in addition to finding potential sites for gene expression regulation. In this study, we focused on the grin1b gene of Zebrafish due to its important...
Recent physiological investigations examining the cardiac calcium handling abilities of tuna and rainbow trout suggest increased reliance on sarcoplasmic reticulum calcium contribution for heart contractility that is both temperature and frequency...
