Considering the pleiotropic manifestations of the rare, inherited, bone marrow failure disease, Fanconi Anemia, afflicted patients must be evaluated and monitored by specialty physicians (such as dermatologists, opthamologists, gastroenterologists,...
The RNA molecule is responsible for providing information to the cell to assemble proteins specified by the DNA. A specific type of RNA editing can convert individual adenosines into inosine by an enzyme called adenosine deaminase acting on RNA...
Cell Migration is an integral part of normal biological development and biological processes, but also plays an important role in pathogenic processes including the progression of cancer towards metastasis. The mechanisms that regulate cell...
The ability of cells to migrate is important for development, neurite formation,
immune function, and other processes necessary for the life of an organism. However,
the gaining of an inappropriate migratory function, as well as, uncontrolled...
Our lab has recently observed a triphasic hypertonicity induced current in stage IV-VI Xenopus laevis oocytes. This current is a calcium-dependant chloride current which is similar to that observed by (Hartzell, 1996). Hartzell, 1996) found that...
The prophage of bacteriophage P1 is a unit copy plasmid, stable in Escherichia coli during cell division due to its partition system. The active P1 partition system consists of two genes, parA and parB, and a cis-site, parS. ParS contains all of...
Minor histocompatibility (H) antigens are typically identified as barriers to transplantation in graft exchange experiments between major histocompatibility complex (MHC)-matched hosts (Bailey 1975; Snell and Bunker 1960). This approach has allowed...
The tick has ability to transmit a greater variety of infectious agents to humans and other animal species than any other blood-feeding arthropod. Feeding over a period of days induces specific host hemostatic, inflammatory, and immune responses....
Myogenesis is an important process that occurs during the developmental stages of an embryo. Stem cells learn of their fate during this course if they will become muscle cells and from there, differentiation within those muscle cells will take...
Receptor-mediated endocytosis as a route of gene delivery shows promise as it is a natural cellular process and allows targeting of ligands to specific cells. A carrier system consisting of two important components: a targetable ligand,...
A-to-I RNA editing is an enzymatic reaction commonly found in the nervous system of various organisms. The mechanism behind this post-transcriptional modification is the hydrolytic deamination of Adenosine to Inosine by a family of enzymes known as...
