The recessive male sterility and histoincompatibility mutation (mshi) in the mouse generates pleiotropic effects on graft transplantation and male reproduction. Previous analysis of backcross mice using a large set of microsatellite markers has...
Rats lacking normal hairy coats were discovered several years ago among our colony of hairy albino rats. The trait was found to be controlled by a recessive allele of a gene we designated shorn (shn), which mapped to distal end of rat chromosome 7....
The frizzy (fr) mutation in Mus musculus affects hair structure and formation. Early studies demonstrated that the gene responsible for frizzy assorts to mouse Chromosome 7 along with pink-eyed dilution (p), chinchilla (cch), and shaker-1 (sh-1). ...
The male sterility and histoincompatibility mutation (mshi) is an autosomal recessive mutation that produces apparently pleiotropic effects in mice. Mice homozygous for mshi manifest two distinct phenotypes. In both male and female mice, the...
Considering the pleiotropic manifestations of the rare, inherited, bone marrow failure disease, Fanconi Anemia, afflicted patients must be evaluated and monitored by specialty physicians (such as dermatologists, opthamologists, gastroenterologists,...
