Ahearn et al. (J. Heredity 93:210-213) have previously shown that the rat fuzzy and Charles River "hairless" mutations are defects in the same gene on rat Chromosome 1, and are likely orthologues of mouse frizzy (abbreviated fr) on mouse Chromosome...
Cell migration is an essential part of many processes including embryonic development, wound healing, and unwanted processes like metastasis. Further study of cell migration is needed to help understand these processes. A cell model system (F9...
Minor histocompatibility (H) antigens are typically identified as barriers to transplantation in graft exchange experiments between major histocompatibility complex (MHC)-matched hosts (Bailey 1975; Snell and Bunker 1960). This approach has allowed...
The frizzy (fr) mutation in Mus musculus affects hair structure and formation. Early studies demonstrated that the gene responsible for frizzy assorts to mouse Chromosome 7 along with pink-eyed dilution (p), chinchilla (cch), and shaker-1 (sh-1). ...
The male sterility and histoincompatibility mutant, mshi, results from a recessive mutation that arose spontaneously in the BALB/cBy inbred mouse strain. Using a 402-member BALB/cBy-mshi/mshi (BALB/cBy-mshi C57BL/6J) F1 backcross panel, the...
The male sterility and histoincompatibility mutation (mshi) is an autosomal recessive mutation that produces apparently pleiotropic effects in mice. Mice homozygous for mshi manifest two distinct phenotypes. In both male and female mice, the...
The mouse frizzy (fr) mutation arose on a genetically mixed background and was first described by G.D. Snell of The Jackson Laboratory in 1951. Mice carrying this recessive mutation have curly vibrissae which can be observed as early as one to two...
The mouse frizzy (fr) mutation is a Mendelian recessive trait that affects hair structure and formation in mice. The mutation arose in a mouse of mixed origin at the Jackson Lab (Bar Harbor, ME) in 1951. Frizzy is known to be linked to other genes...
The recessive male sterility and histoincompatibility mutation (mshi) in the mouse generates pleiotropic effects on graft transplantation and male reproduction. Previous analysis of backcross mice using a large set of microsatellite markers has...
The RNA molecule is responsible for providing information to the cell to assemble proteins specified by the DNA. A specific type of RNA editing can convert individual adenosines into inosine by an enzyme called adenosine deaminase acting on RNA...
