During the development of potential protein or antibody therapeutics in a pharmaceutical environment, the use of animal models as test subjects is a necessary requirement. The dosing of mice, rats, and primates is essential to drug development...
The autosomal recessive mshi mutation in BALB/cBy mice phenotypically causes reduced testis size and male sterility in homozygotes. The development of the mshi male generative organs, prior to three weeks of age, appears to lack observable...