Infertility is a common problem, affecting approximately 10% of all couples attempting to conceive (Watson et al., 1998). Although numerous potential causes of human infertility exist, many cases are thought to have genetic etiologies, including...
The male sterility and histoincompatibility mutant, mshi, results from a recessive mutation that arose spontaneously in the BALB/cBy inbred mouse strain. Using a 402-member BALB/cBy-mshi/mshi (BALB/cBy-mshi C57BL/6J) F1 backcross panel, the...
Human reproductive technology; Fertilization in vitro, Human
The purpose of this study was to evaluate the outcome of Intracytoplasmic Sperm Injection (ICSI) in patients with previous unexplained fertilization failure (≤20%) after conventional in vitro fertilization (IVF) in our program and to compare them...
The recessive male sterility and histoincompatibility mutation (mshi) in the mouse generates pleiotropic effects on graft transplantation and male reproduction. Previous analysis of backcross mice using a large set of microsatellite markers has...